Types of EC

There are two main types of esophageal cancer.

Cancer of the esophagus can start anywhere along the length of the esophagus.  Each develops in a different kind of cell.

  • Squamous cell carcinoma: the most common type of esophageal cancer worldwide. South Central Asia’s “esophageal cancer belt” region is reported as having some of the highest rates of esophageal squamous cell carcinoma worldwide, affecting both males and females at similar rates. Squamous cell carcinoma starts in the squamous cells that line the esophagus. These cancers are usually found in the upper and middle part of the esophagus. Normally these cancers are caused by heavy alcohol consumption and smoking, but there have been other documented risk factors as well.


  • Adenocarcinoma: the most common type in the United States and in Western Europe. Esophageal adenocarcinoma is one of the fastest increasing of all cancers in the United States.  Adenocarcinoma starts in the glandular cells in the lower part of the esophagus and may occur at or near the junction of the esophagus and the stomach, known as the gastroesophageal (GE) – junction. Normally these cancers are caused by Acid Reflux and are linked to obesity.


Other Types of EC?

Other Esophageal Cancers: Rare forms of esophageal cancer include choriocarcinoma, lymphoma, melanoma, sarcoma and small cell cancer. Various other types of esophageal cancer like the small cell carcinoma, lymphoma and spindle cell carcinoma are not observed in patients very often but are seen very rarely. Normally these rare types of esophageal cancer might be caused due to the spreading of cancer from various other body parts,  like lungs or breasts, and into the esophagus via lymph system or via blood stream.Close

Different Types, Different Reasons

Each type of Esophageal Cancer has its own set of risk factors, symptoms and treatments.

Source: Mayo Clinic

Last updated: April 30, 2012 at 17:39 pm

Privacy Policy: The personal information collected from the visitors of our website, including their identity, remains confidential. We respect the law(s) on confidentiality applicable to this website (hosting country) and we will never pass on these data to any third party, unless required by law. Our website does not collect any cookies. The ECAA is registered with the Health on the Net (HON) Organization.
The Esophageal Cancer Awareness Association, Inc. (ECAA) is a New York State non profit corporation which is recognized as tax exempt under Section 501(c)(3) of Internal Revenue Code.

Disclaimer: This information contained in this site is for educational purposes only. The information here cannot and should not replace the guidance and opinions of your medial professional. The the authors, webmaster, the ECAA and other parties affiliated to the site have no responsibility for visitors' use of this site and/or any subsequent medical decisions or treatment.